Effect of Letrozole on sperm parameters, chromatin status and ROS level in idiopathic Oligo/Astheno/Teratozoospermia
نویسندگان
چکیده
منابع مشابه
effect of varicocelectomy on semen parameters and sperm chromatin status
introduction: different methods have been used to evaluate the beneficial effect of varicocelectomy; these include semen parameters and pregnancy rate. due to high biological variability of semen parameters, sperm functional test has been considered an efficient end point in assessment of fertility. therefore, the aim of this study was to evaluate the effect of varicocelectomy on semen paramete...
متن کاملEffect of High Light Level on Sperm parameters in Mice
Background and aims: High light level of natural or artificial sources in some workplaces may be considered as a hazardous physical agent. The present study aimed to assess the effect of light level of 1000 lux on sperm parameters in mice. Methods: The subjects were assessed in two group including 1. Exposed (n= 6; exposed to light level of 1000 lux during 5 eight-hour days), 2. Unexposed ...
متن کاملEffect of PolyVinyl Pyrrolidone on Sperm Membrane Integrity and Chromatin Status
Background The aim of present study is to evaluate the effect of PolyVinyl Pyrrolidone (PVP) routinly used during ICSI procedure on sperm membrane integrity, and sperm chromatin status. MaterialsAndMethods This study was carried out on 21 semen samples from the infertile men referring to Isfahan Fertility and Infertility Center. The processed semen samples were divided into two portions. One po...
متن کاملCombination effect of Pentoxifylline and L-carnitine on idiopathic oligoasthenoteratozoospermia
BACKGROUND Pentoxifylline (PX) is a methyl xanthine derivative that influences the sperm motion characteristics and L-carnitine (L-C) is an amino acid that is naturally produced in the body. In general, separate administration of PX and L-C has been reported to be effective on preserving sperm motility in vitro, and also when is consumed orally by the Idiopathic oligoasthenoteratozoospermia (IO...
متن کاملP-19: Association of Poor Chromatin Remodeling with Cytosolic ROS and Mitochondrial ROS in Sperm of Infertile Men
Background: Cytoplasm and mitochondria are considered as the major origins of sperm ROS production. Sperm is prone to DNA damage by exposure to ROS or due impaired chromatin remodeling or low DNA protamination. Therefore, the aim of this study was to see if there is any association between impaired chromatin packaging and origin of ROS production. Materials and Methods: Cytosolic ROS, mitochond...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Reproductive Biology and Endocrinology
سال: 2020
ISSN: 1477-7827
DOI: 10.1186/s12958-020-00591-2